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Oligourethano Isoméricos Definidos por Secuencia para Cifrado Irreversible

Lingxiao Guo¹, Qiangqiang Shi¹, Jin Zhang¹

¹State Key Laboratory of Precision and Intelligent Chemistry, Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei, Anhui, China.

Angewandte Chemie (International ed. in English)

|February 19, 2026

Resumen

Este estudio presenta mezclas isoméricas de oligourethano definidos por secuencia (SDOs) para el cifrado molecular seguro de datos. Estas mezclas crean un cifrado irreversible, ofreciendo un nuevo enfoque para la seguridad de datos y la lucha contra la falsificación.

Área de la Ciencia:

Química de Polímeros
Criptografía Molecular
Seguridad de la Información

Sus antecedentes:

Se exploran los polímeros definidos por secuencia (SDPs) para el almacenamiento y cifrado de datos.
Los métodos actuales se basan en síntesis complejas (por ejemplo, cadenas más largas, monómeros diversos).
Necesidad de estrategias de cifrado molecular más simples y seguras.

Objetivo del estudio:

Introducir un novedoso mecanismo de cifrado utilizando mezclas isoméricas de oligourethano definidos por secuencia (SDOs).
Demostrar un proceso de cifrado molecular intrínsecamente unidireccional e irreversible.
Desarrollar una plataforma escalable para la seguridad de datos de próxima generación y la lucha contra la falsificación.

Principales métodos:

Se utilizaron mezclas isoméricas de oligourethano definidos por secuencia (SDOs).
Se empleó MALDI-TOF MS para demostrar la identidad composicional oculta debido a pesos moleculares idénticos.
Se aplicó la fragmentación en tándem MS/MS para generar rutas de decodificación degeneradas.
Se integraron mezclas en tintas digitales moleculares CMYK para impresión y transmisión.

Principales resultados:

Las mezclas isoméricas de SDO colapsan en un solo pico en MALDI-TOF MS, ocultando la composición.
La fragmentación en tándem MS produce múltiples vías de decodificación no únicas, lo que impide la reconstrucción.
Demostración de prueba de concepto con cuatro isómeros octaméricos del principio de cifrado.
Integración exitosa en tintas CMYK para la transmisión segura de información.

Conclusiones:

Las mezclas de oligómeros isoméricos representan una nueva clase de medios criptográficos moleculares.
El método ofrece un cifrado molecular intrínsecamente unidireccional e irreversible.
Este enfoque une el diseño químico con la teoría de la información para una seguridad de datos avanzada.

Palabras clave:

MS/MS de MALDI-TOF cifrado irreversible mezcla isomérica decodificación de secuencias oligourethano definido por secuencia

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