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Updated: Feb 20, 2026

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Una evaluación crítica del vínculo entre la apolipoproteína E y Tau

Sudeshna Das1,2,3, Bradley T Hyman1,2,3, Alberto Serrano-Pozo1,2,3

  • 1Mass General Brigham Neurology Department, Boston.

Current opinion in neurology
|February 19, 2026
PubMed
Resumen

El alelo ε4 de la apolipoproteína E (APOE) influye en la patología tau de la enfermedad de Alzheimer (EA) independientemente de la beta-amiloide. Se necesita más investigación para comprender completamente la conexión APOE-tau en la EA y otras tauopatías.

Palabras clave:
apolipoproteína Eastrocitosmicroglíaovillo neurofibrilartaupatía

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