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Cardiomiopatía Arritmogénica del Ventrículo Derecho Inducida por Quimioterapia
Ahmed Al Mubaid1, Muhammad Baba1, Vishak Vinod1
1Franciscan Hospital, Midwestern University, Olympia Field, Illinois, USA.
JACC. Case reports
|February 19, 2026
Resumen
La quimioterapia con antraciclinas puede causar miocardiopatía arritmogénica del ventrículo derecho (ARVC), una afección típicamente hereditaria. Este caso destaca la necesidad de estar alerta ante la disfunción del ventrículo derecho después de la quimioterapia.
Área de la Ciencia:
- Cardiología; Oncología; Farmacología
Sus antecedentes:
- La miocardiopatía arritmogénica del ventrículo derecho (ARVC) es una afección cardíaca hereditaria.; Implica la sustitución del ventrículo derecho por tejido fibroadiposo.; La quimioterapia con antraciclinas generalmente afecta al ventrículo izquierdo.
Objetivo del estudio:
- Presentar un caso único de fenotipo de ARVC adquirida.; Relacionar este fenotipo con la exposición a quimioterapia con antraciclinas.
Principales métodos:
- Un paciente varón de 74 años presentó síncope.; Había recibido quimioterapia a base de antraciclinas.; El diagnóstico de ARVC se basó en criterios establecidos, a pesar de las pruebas genéticas negativas.
Principales resultados:
- El paciente cumplió los criterios de ARVC definida.; Se le implantó con éxito un desfibrilador.; El síncope se resolvió por completo después de la implantación.
Conclusiones:
- La exposición a antraciclinas puede provocar un fenotipo de ARVC adquirida.; Esto amplía la comprensión de las miocardiopatías relacionadas con la quimioterapia.; Es crucial estar alerta ante la disfunción del ventrículo derecho después de la quimioterapia.
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