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Updated: Feb 20, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Published on: June 13, 2021

Impacto del estrés psicosocial en el desarrollo infantil

Marine Jequier Gygax¹, Karine Sofia Scherrer², Gëatan Zwingli^3,4

¹Vidymed, Route de Chavannes 9, 1007 Lausanne.

Revue medicale suisse

|February 19, 2026

Abstract:

When caregivers are unable to meet their children's needs, psychosocial stress may affect the children's neurodevelopment. Even before or during pregnancy, parental stress is associated with alterations in fetal brain development that may affect later neurodevelopment. Moreover, while parental attitudes and beliefs about child-rearing may impact neurodevelopment (sleep, physical activity, screen time), neurodevelopmental disorders may also affect family mental health. The interaction between psychosocial stress and child neurodevelopment is bidirectional and warrants careful monitoring by primary care health professionals, as suboptimal parenting may hinder the treatment of learning disorders. Thus, early detection and scaffolding of the family structure are key.

Palabras clave:

estrés parental neurodesarrollo infantil desarrollo fetal detección temprana apoyo familiar

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