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Dos casos pediátricos de enfermedad de Kimura tras la vacunación
Sosuke Kakee1, Hiroaki Funata2, Keisuke Okuno1
1Division of Perinatology and Pediatrics, School of Medicine, Faculty of Medicine, Tottori University, Yonago 683-8504, Japan.
Yonago acta medica
|February 19, 2026
Resumen
La enfermedad de Kimura, una afección inflamatoria crónica, puede presentarse como una masa indolora después de la vacunación en niños. El diagnóstico temprano es crucial para el tratamiento y manejo oportunos de este raro trastorno.
Área de la Ciencia:
- Inmunología
- Pediatría
- Patología
Sus antecedentes:
- La enfermedad de Kimura es un trastorno inflamatorio crónico.
- Se caracteriza por eosinofilia, IgE elevada y masas indoloras.
- Los casos pediátricos son menos comunes pero se han notificado.
Objetivo del estudio:
- Informar sobre dos casos pediátricos de enfermedad de Kimura.
- Destacar el posible vínculo entre la vacunación y la enfermedad de Kimura en niños.
- Enfatizar la importancia de diferenciar la enfermedad de Kimura de la IgG4-RD.
Principales métodos:
- Informe de caso de dos pacientes pediátricos.
- Análisis de la presentación clínica, incluidos los eventos adversos posteriores a la vacunación.
- Consideraciones diagnósticas para la enfermedad de Kimura.
Principales resultados:
- Dos casos pediátricos de enfermedad de Kimura diagnosticados después de la vacunación.
- La presentación incluyó ganglios linfáticos inflamados en el cuello y las extremidades superiores.
- Masa asociada a la vacunación como una pista diagnóstica potencial.
Conclusiones:
- Una masa indolora después de la vacunación puede indicar enfermedad de Kimura en niños.
- Es importante diferenciar la enfermedad de Kimura de la enfermedad relacionada con IgG4.
- El diagnóstico temprano en pacientes pediátricos es vital para un manejo eficaz.
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