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Identificación de Síntomas Centrales en Pacientes con Cáncer de Mama con Diferentes Fases de Quimioterapia Mediante
Jiali He1, Dingxi Bai1, Huan Chen1
1School of Nursing, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, People's Republic of China.
Patient preference and adherence
|February 19, 2026
Resumen
Este estudio identificó los síntomas centrales en pacientes con cáncer de mama en tratamiento de quimioterapia. Las intervenciones deben dirigirse inicialmente a la dificultad para dormir y la depresión, seguidas de la disminución del apetito y el dolor, siendo la fatiga central en las etapas posteriores.
Área de la Ciencia:
- Oncología
- Ciencia de los Síntomas
- Análisis de Redes
Sus antecedentes:
- El análisis de redes ayuda a identificar síntomas centrales para estrategias de tratamiento dirigidas en el cáncer de mama.
- Existe una investigación limitada sobre redes de síntomas en diferentes fases de la quimioterapia para pacientes con cáncer de mama.
Objetivo del estudio:
- Identificar síntomas centrales para la intervención en distintas fases de la quimioterapia en pacientes con cáncer de mama.
Principales métodos:
- Una encuesta longitudinal prospectiva multicéntrica incluyó a 467 pacientes con cáncer de mama de noviembre de 2022 a octubre de 2023.
- La Escala de Evaluación de Síntomas para Pacientes con Cáncer de Mama que Reciben Quimioterapia midió los síntomas en cuatro momentos: pre-quimioterapia (T0), después del primer (T1), tercer (T2) y sexto (T3) tratamiento.
- El análisis de redes exploró las redes de síntomas y las propiedades de los nodos.
Principales resultados:
- En T0, la dificultad para dormir y la depresión fueron síntomas clave.
- En T1, la disminución del apetito y el dolor emergieron como preocupaciones principales.
- La fatiga se identificó como el síntoma más central en T2 y T3, observándose redes de síntomas estables a lo largo del estudio.
Conclusiones:
- Los síntomas centrales que requieren intervención varían según las etapas de la quimioterapia en pacientes con cáncer de mama.
- Las intervenciones específicas deben abordar la dificultad para dormir y la depresión (T0), la disminución del apetito y el dolor (T1), y priorizar el manejo de la fatiga en etapas posteriores (T2, T3).
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