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Dando forma al futuro de la terapia dirigida a HER2 en el cáncer de vías biliares
Orla M Fitzpatrick1, James J Harding1
1Memorial Sloan Kettering Cancer Center New York, NY United States.
Abstract:
This commentary on a retrospective study of patients with HER2 positive biliary tract cancer highlights the importance of reflex and validated HER2 testing criteria; the discordance of next generation sequencing and HER2 immunohistochemistry; the potential prognostic and predictive role of HER2; and the necessity to define HER2 therapy resistance mechanisms.
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