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Updated: May 5, 2026

Modification and Functionalization of the Guanidine Group by Tailor-made Precursors
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Published on: April 27, 2017

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Un modulador alostérico negativo subunitario selectivo del receptor activado por glicina GluN1/GluN3A

Leon Jacobs1, TrangKimberly T Nguyen2, Adam McCallum1

  • 1Department of Chemistry, Emory University, Atlanta, Georgia.

Molecular pharmacology
|February 19, 2026
PubMed
Resumen

Los investigadores descubrieron compuestos novedosos que inhiben selectivamente los receptores GluN1/GluN3A, a diferencia de los moduladores anteriores. Estos inhibidores selectivos ofrecen nuevas herramientas para estudiar la función cerebral y desarrollar tratamientos para trastornos neurológicos.

Palabras clave:
GluN3AReceptor de glicinaNMDARModulador alostérico negativo

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