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Trastornos pediátricos de interacción cerebro-intestino del tracto gastrointestinal superior según Roma V
Rachel Rosen1, Osvaldo Borelli2, Christophe Faure3
1Center for Motility and Functional Gastrointestinal Disorders, Division of Gastroenterology, Children's Hospital Boston, Boston, Massachusetts, USA.
Abstract:
Upper gastrointestinal Disorders of Gut-Brain Interaction (DGBI) present from infancy through adolescence. The Rome V criteria have expanded to include DGBI of the esophagus, disorders of air-transit and feeding disorders as well as rumination syndrome, cyclic vomiting, chronic nausea syndrome and functional dyspepsia. This expansion provides a diagnostic framework for patients presenting with chest and throat pain, feeding difficulties, belching, pain with eating, nausea and vomiting. Given the advances in impedance technology and high-resolution manometry, testing plays a greater role in these diagnostic criteria than they have in past Rome iterations. This harmony between symptoms and testing results in more precision in therapeutic approaches that are critically multidisciplinary. The ability to assign new, positive diagnoses across the upper gastrointestinal tract offers new opportunities for pediatric-focused therapeutic trials.
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