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Antioxidantes redoxactivos permiten sistemas bio-electroqímicos altamente estables

Wei Chen¹, Rui Bai², Biyi Zhao¹

¹State Key Laboratory of Regional and Urban Ecology, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, China; University of Chinese Academy of Sciences, Beijing 100049, China.

Bioresource technology

|February 19, 2026

Resumen

Los antioxidantes vegetales como la fraxetina actúan como lanzaderas de electrones robustas, manteniendo el rendimiento de las células de combustible microbianas a pesar de la exposición al oxígeno. Esto supera las limitaciones de los métodos tradicionales para aplicaciones energéticas y medioambientales.

Área de la Ciencia:

Biotecnología
Electroquímica
Ciencias Ambientales

Sus antecedentes:

La transferencia de electrones interfacial eficiente es crucial para los sistemas bio-electroqímicos (BES) en aplicaciones energéticas, medioambientales y bioelectrónicas.
La infiltración de oxígeno perjudica gravemente el rendimiento de los BES al alterar los procesos de transferencia de electrones.

Objetivo del estudio:

Investigar antioxidantes de origen vegetal como lanzaderas de electrones estables para BES.
Evaluar la eficacia de la fraxetina en el mantenimiento de la transferencia de electrones bajo exposición a oxígeno.

Principales métodos:

Se realizó análisis electroquímico para evaluar la eficiencia de la transferencia de electrones.
Se utilizó la teoría de funcionales de la densidad (DFT) para comprender la estabilidad termodinámica y las propiedades redox de las lanzaderas de electrones.
Se realizaron estudios comparativos utilizando Shewanella oneidensis MR-1 con mononucleótido de flavina y fraxetina como mediadores de electrones bajo diversas condiciones de oxígeno.

Principales resultados:

La fraxetina demostró alta estabilidad termodinámica y resistencia a la oxidación por oxígeno, a diferencia del mononucleótido de flavina.
La transferencia de electrones mediada por fraxetina mostró solo una disminución del 18% en la corriente bajo oxígeno disuelto saturado.
En contraste, la transferencia de electrones mediada por mononucleótido de flavina experimentó una disminución del 75% en la corriente en condiciones similares.

Conclusiones:

La fraxetina sirve como una lanzadera de electrones robusta y tolerante al oxígeno, lo que permite una transferencia de electrones interfacial sostenida en BES.
Esta estrategia basada en antioxidantes ofrece una alternativa práctica a los métodos físicos de exclusión de oxígeno para aplicaciones BES en el mundo real.

Palabras clave:

Antioxidantes Sistemas bio-electroqímicos Lanzaderas de electrones Infiltración de oxígeno Shewanella oneidensis MR-1

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