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Revisión de la terapia radiometabólica en el cáncer de próstata

Sean R Miller¹, Yuni Dewaraja², Steven P Rowe³

¹Department of Radiation Oncology, University of Michigan, Ann Arbor, MI; Department of Radiology, Division of Nuclear Medicine, University of Michigan, Ann Arbor, MI.

Urologic oncology

|February 19, 2026

Abstract:

Radiopharmaceuticals therapy (RPT) has been a major breakthrough in the treatment of prostate cancer. This therapy utilizes radioactive isotopes targeted specifically to prostate cancer, combining the advantages of systemic therapy with targeted radiation. The 2 currently FDA approved agents are ²²³Ra and ¹⁷⁷Lu-PSMA-617 which have both demonstrated an overall survival advantage. In this review we will discuss the approved agents, their similarities and differences, treatment sequencing, combinations with other therapies, as well as future directions of this promising field.

Palabras clave:

Cáncer de próstata Terapia de radioligando Teranóstica

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