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Diabetes, obesidad y los impulsores metabólicos de la enfermedad arterial periférica: lecciones de pronósticos

Edward Jude^1,2, Hongyan Wang³

¹Department of Diabetes and Endocrinology, University of Manchester, Manchester, UK.

Vascular health and risk management

|February 20, 2026

Resumen

La enfermedad arterial periférica (PAD) afectará a más de 360 millones de personas en 2050, impulsada por el aumento de las tasas de diabetes y obesidad. Las estrategias urgentes dirigidas a la salud metabólica son cruciales para prevenir una crisis de salud global.

Área de la Ciencia:

Salud Cardiovascular La salud cardiovascular.
Enfermedades Metabólicas Las enfermedades metabólicas.
Epidemiología de la salud global Epidemiología de la salud global.

Sus antecedentes:

La enfermedad arterial periférica (EAP) es un problema de salud mundial cada vez mayor.
Las proyecciones indican un aumento significativo en la prevalencia, la mortalidad y la discapacidad de la EAP para 2050.
Las enfermedades metabólicas, particularmente la diabetes y la obesidad, se identifican como los principales impulsores de esta tendencia.

Objetivo del estudio:

Para resaltar la interacción crítica entre los factores de riesgo metabólicos y la progresión de la EAP.
Para subrayar la carga desproporcionada de PAD esperada en los países de ingresos bajos y medios.
Para pedir estrategias urgentes e integradas dirigidas a la salud metabólica para mitigar la crisis de PAD.

Principales métodos:

Análisis de estudios recientes basados en la población y pronósticos sobre la carga global de PAD.
Revisión de los datos epidemiológicos que vinculan las enfermedades metabólicas con la prevalencia de la EAP.
Comentario que sintetiza la evidencia sobre el impacto de la salud metabólica en la progresión de la EAP.

Principales resultados:

Se prevé que la prevalencia de la EAP aumente en aproximadamente un 220%, afectando a más de 360 millones de personas en todo el mundo a mediados de siglo.
Las enfermedades metabólicas, especialmente la diabetes y la obesidad, son los factores dominantes de la creciente carga de la EAP.
Se espera que los países de bajos y medianos ingresos soporten una parte desproporcionada de la futura carga de PAD.

Conclusiones:

Abordar la creciente crisis mundial de PAD requiere una acción decisiva para reducir la diabetes, la obesidad y los trastornos metabólicos relacionados.
Las estrategias integradas dirigidas a la salud metabólica son esenciales para evitar una mayor tensión en los sistemas de atención médica y el empeoramiento de las desigualdades en salud.
La falta de acción decisiva exacerbará la crisis mundial de PAD, afectando a los sistemas de salud y profundizando las disparidades de salud en todo el mundo.

Palabras clave:

PAD PAD es el nombre que se le da a las Las personas con diabetes son personas con diabetes.Obesidad obesidad.enfermedad de las arterias periféricas.

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