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PEComa maligno retroperitoneal: reporte de caso

Abigail McKenzie¹, Racha Cherradi¹, Maleeha Ahmad¹

¹College of Medicine, Texas A&M University, College Station, Texas, USA.

Proceedings (Baylor University. Medical Center)

|February 20, 2026

Resumen

Este resumen es generado por máquina.

Los tumores de células epitelioides perivasculares (PEComas) son neoplasias mesenquimales raras. Este caso destaca un PEComa retroperitoneal maligno con metástasis, enfatizando las consideraciones diagnósticas y de tratamiento.

Palabras clave:

Maligno PEComa TSC mTOR retroperitoneal

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Área de la Ciencia:

Oncología
Patología

Sus antecedentes:

Los tumores de células epitelioides perivasculares (PEComas) son neoplasias mesenquimales raras caracterizadas por un fenotipo inmunoquímico miomelanocítico único.
Estos tumores afectan predominantemente a adultos, con predilección por las mujeres, y pueden surgir en diversas localizaciones anatómicas.
Si bien la mayoría de los PEComas son benignos con buen pronóstico, las variantes malignas pueden comportarse agresivamente.

Objetivo del estudio:

Presentar una viñeta clínica de un PEComa maligno.
Ilustrar los desafíos diagnósticos y las implicaciones del tratamiento del PEComa metastásico.

Principales métodos:

Reporte de caso de una mujer de 65 años con PEComa maligno retroperitoneal.
Revisión de la presentación clínica, hallazgos diagnósticos y consideraciones de tratamiento.

Principales resultados:

El paciente presentó un PEComa maligno en el retroperitoneo.
Se desarrolló enfermedad metastásica, subrayando el potencial agresivo del PEComa maligno.
El diagnóstico preciso es crucial para un manejo apropiado.

Conclusiones:

Los PEComas malignos, aunque poco comunes, pueden presentarse agresivamente con potencial metastásico.
Este caso enfatiza la importancia de reconocer el PEComa y considerar su potencial maligno en la planificación del diagnóstico y tratamiento.