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Updated: Feb 22, 2026

Detecting the Lyme Disease Spirochete, Borrelia Burgdorferi, in Ticks Using Nested PCR
Published on: February 4, 2018
Prácticas de prescripción de profilaxis postexposición en un área endémica de la enfermedad de Lyme
Eun Bin Lee1, Anna Schotthoefer2, Philip Whitfield1
1Department of Pharmacy, Marshfield Clinic Region-Sanford Health, Marshfield, WI 54449, USA.
En áreas endémicas de la enfermedad de Lyme, las prácticas de prescripción de profilaxis con doxiciclina a menudo carecen de documentación clara y adherencia a las directrices. Esto resalta la necesidad de mejorar la prescripción y documentación basadas en la evidencia en los entornos de atención médica.
Área de la Ciencia:
- Infectious Diseases; Public Health; Clinical Practice Guidelines
Sus antecedentes:
- The Infectious Diseases Society of America (IDSA) guidelines suggest doxycycline for Lyme disease prophylaxis after tick bites.; Data on current prescribing practices for Lyme disease prevention in high-risk areas are limited.
Objetivo del estudio:
- To evaluate doxycycline prescribing practices for Lyme disease prophylaxis in a rural Wisconsin health system.; To assess adherence to IDSA guidelines and identify documentation issues.
Principales métodos:
- Retrospective chart review of adult patients receiving doxycycline for Lyme disease prevention (2022-2024).; Analysis of patient and provider characteristics.; Manual data abstraction of 155 prescriptions to assess guideline concordance.
Principales resultados:
- 2404 prescriptions were analyzed; most were for older adults and males in rural areas, peaking in warmer months.; Prescribing occurred across provider types, predominantly in outpatient/urgent care.; Only 12% of prescriptions had clear indications; others had suboptimal documentation or nonadherence.
Conclusiones:
- Significant rates of incomplete documentation and uncertainty in guideline adherence were found.; Opportunities exist to enhance evidence-based prescribing and improve documentation for Lyme disease prophylaxis.
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