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UN MAPA CORPORAL ELECTRÓNICO AUTO-REPORTADO IDENTIFICA FENOTIPOS DE DOLOR CLÍNICO DISTINTOS EN LA PANCREATITIS
Jorge D Machicado1, David Guevara-Lazo1, Jonathan P Troost2
1Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, MI.
Clinical and translational gastroenterology
|February 20, 2026
Resumen
El dolor generalizado, identificado mediante un simple mapa corporal en pacientes con pancreatitis crónica (PC), se asocia con síntomas más graves y características de dolor nociceptivo. Esta herramienta puede ayudar a adaptar las estrategias de manejo del dolor para la PC.
Área de la Ciencia:
- Gastroenterología
- Medicina del Dolor
- Neurología
Sus antecedentes:
- La pancreatitis crónica (PC) puede causar dolor nociceptivo debido a la desregulación del sistema nervioso central.
- El diagnóstico de dolor nociceptivo en la PC es un desafío debido a la falta de herramientas a pie de cama.
- Los mapas corporales evalúan la extensión del dolor en el dolor crónico, pero su uso en la PC no está bien establecido.
Objetivo del estudio:
- Investigar la asociación entre la extensión del dolor, medida por un mapa corporal, y las características del dolor nociceptivo en pacientes con PC.
Principales métodos:
- Se realizó un análisis transversal de 110 adultos con PC definida.
- La extensión del dolor se evaluó utilizando el Mapa Corporal de Michigan, clasificando el dolor como localizado o generalizado (≥3 regiones).
- Se midieron las características clínicas del dolor nociceptivo mediante encuestas validadas, y se realizaron análisis de regresión multivariable.
Principales resultados:
- El 64 % de los pacientes con PC y dolor abdominal reportaron dolor generalizado.
- El dolor generalizado se correlacionó con un aumento de la gravedad del dolor, la interferencia del dolor y las puntuaciones de dolor neuropático.
- El dolor generalizado también se asoció con mayor fatiga, deterioro de la función física, condiciones de dolor crónico superpuestas y peores resultados de salud.
Conclusiones:
- Una proporción significativa de pacientes con PC presenta dolor generalizado, identificable a través de un mapa corporal.
- Este subgrupo presenta síntomas más graves e indicadores de dolor nociceptivo.
- Un mapa corporal puede servir como una herramienta práctica para identificar pacientes que podrían beneficiarse de un manejo del dolor específico y basado en mecanismos en la PC.
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