Video Experimental Relacionado

Updated: Feb 22, 2026

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
07:16

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission

Published on: August 16, 2018

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Avances recientes en ligandos dirigidos al receptor GABAA

Yuanyan Zuo1, Yilan Zhao2, Genyan Liu1

  • 1Hubei Key Laboratory of Novel Reactor and Green Chemical Technology, Key Laboratory for Green Chemical Process of Ministry of Education, School of Chemical Engineering and Pharmacy, Wuhan Institute of Technology, Wuhan, 430205, PR China.

European journal of medicinal chemistry
|February 20, 2026
PubMed
Resumen

El receptor γ-aminobutírico tipo A (GABAA) es clave para la inhibición cerebral. Las nuevas perspectivas estructurales de la crio-EM están guiando el desarrollo de fármacos dirigidos para trastornos neuropsiquiátricos.

Palabras clave:
moduladores alostéricosestructuras crio-EMreceptor GABA(A)trastornos neuropsiquiátricosdiseño de fármacos basado en la estructuraselectividad de subtipos

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