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Explorando los cambios relacionados con la edad en los huesos y músculos: Perspectivas de la radiómica y la

Maryam Elikaei Moghadam¹, Elmira Yazdani¹, Mohammad Bagher Shiran¹

¹Medical Physics Department, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

Journal of medical imaging and radiation sciences

|February 22, 2026

Resumen

La imagen por resonancia magnética (IRM) radiómica puede detectar cambios musculares y óseos relacionados con la edad. Las características basadas en la textura en los músculos de las piernas se correlacionan con el envejecimiento y el deterioro óseo, lo que ayuda al monitoreo temprano de la salud musculoesquelética.

Área de la Ciencia:

Imágenes del aparato musculoesquelético.
La radiomía es la radiomía.
Investigación sobre el envejecimiento de la investigación.

Sus antecedentes:

El deterioro musculoesquelético relacionado con la edad afecta la salud.
Los métodos actuales pasan por alto los cambios sutiles del envejecimiento óseo y muscular.
Las imágenes de resonancia magnética (IRM) y la radiómica ofrecen un análisis avanzado.

Objetivo del estudio:

Investigar el vínculo entre las características radiómicas del músculo de la pantorrilla y el agua libre del hueso cortical tibial T1 con la edad.
Explorar la radiomía basada en resonancia magnética para evaluar los cambios musculoesqueléticos relacionados con la edad.

Principales métodos:

Estudio de resonancia magnética transversal en 34 adultos sanos (30-62 años).
Segmentación manual de los músculos de la pantorrilla y extracción de 108 características radiómicas.
Cuantificación del agua libre ósea cortical T1 y análisis de correlación con la edad.

Principales resultados:

Se encontraron correlaciones significativas entre las características radiómicas del músculo de la pierna y la edad/agua cortical libre de huesos T1.
Las características radiómicas basadas en la textura mostraron variaciones notables relacionadas con la edad (r > 0,4, p < 0,01).

Conclusiones:

La radiomía basada en RM captura efectivamente los cambios relacionados con la edad en los músculos y huesos de las extremidades inferiores.
La radiómica muestra potencial para el monitoreo del envejecimiento musculoesquelético temprano y la estratificación del riesgo.

Palabras clave:

El hueso cortical es el hueso cortical.Agua libre de agua gratis.Imágenes del aparato musculoesquelético.La radiomía es la radiomía.

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