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Desarrollo de preformulación de agentes potentes contra micobacterias no tuberculosas

Satish G Agrawal1, E Jeffrey North1, Alekha K Dash1

  • 1Department of Pharmacy Sciences, School of Pharmacy and Health Professions, Creighton University, 2500 California Plaza, Omaha, NE 68178, USA.

Results in chemistry
|February 23, 2026
PubMed
Resumen

Los nuevos compuestos de indole-2-carboxamida muestran una promesa contra las infecciones por micobacterias no tuberculosas (NTM). Los estudios de preformulación revelan desafíos con la solubilidad y la permeabilidad, clasificándolos como fármacos de clase II del Sistema de Clasificación Biofarmacéutica.

Palabras clave:
Indole-2-carboxamidasMicobacterias no tuberculosasPolimorfoPreformulaciónEstado sólidoAnálisis térmicos

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