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Updated: Jul 28, 2026

Genome-wide Analysis of HDAC Inhibitor-mediated Modulation of microRNAs and mRNAs in B Cells Induced to Undergo Class-switch DNA Recombination and Plasma Cell Differentiation
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Selección algorítmica en dos pasos de genes de referencia basados en desajustes de secuencias interespecíficas para

Minseong Jo1,2, Seo Yule Jeong1, Mi-Lang Kyun1

  • 1Center for Global Biopharmaceutical Research, Korea Institute of Toxicology, Daejeon 34114, Republic of Korea.

ACS omega
|February 23, 2026
PubMed
Resumen

La selección de genes de referencia estables es vital para el análisis preciso de la expresión génica en modelos de ratón humanizados. Este estudio identifica genes específicos del tejido para células humanas en ratones, mejorando la fiabilidad de la investigación.

Palabras clave:
genes de referenciaexpresión génicamodelos de ratón humanizadoscélulas mononucleares de sangre periférica humanaestabilidad génicaanálisis de expresión génicaratones NSGinmunologíainvestigación biomédicagenética

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