Video Experimental Relacionado

Updated: Feb 24, 2026

Assessing Cellular Target Engagement by SHP2 PTPN11 Phosphatase Inhibitors
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Assessing Cellular Target Engagement by SHP2 PTPN11 Phosphatase Inhibitors

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Actividad significativa de Pytren-2Q, un compuesto de poliamina 2-quinolina, contra hongos patógenos humanos de alta

Mario Inclán1,2, Maria Paz Clares1, Eduardo Álvarez-Duarte3

  • 1Molecular Science Institute, Universitat de València, C/Catedrático José Beltrán 2, 46980 Paterna, Spain.

ACS omega
|February 23, 2026
PubMed
Resumen

Los nuevos compuestos antifúngicos son cruciales debido al aumento de las enfermedades fúngicas invasivas y la resistencia. Un nuevo compuesto, Pytren-2Q, muestra una potente actividad contra patógenos fúngicos prioritarios, incluido Aspergillus fumigatus resistente a los azoles, lo que sugiere un potencial terapéutico.

Palabras clave:
Pytren-2Qpoliamina 2-quinolinaantifúngicopatógenos fúngicosAspergillus fumigatus resistente a los azolesdescubrimiento de fármacos

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