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Updated: Feb 24, 2026
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A Spheroid Killing Assay by CAR T Cells
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Células CAR-T dirigidas por DSG2 eliminan tumores sólidos de forma segura y universal
Research square
|February 23, 2026
Resumen
La terapia de células T con receptores de antígenos quiméricos (CAR-T) muestra una gran promesa para los tumores sólidos al dirigirse a la desmogleína 2 (DSG2). Las células CAR-T dirigidas por DSG2 eliminaron eficazmente diversos tumores sólidos in vivo sin toxicidad observada en modelos preclínicos.
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