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Blastocystis en un Absceso Hepático: Una Localización Extraintestinal Inusual
Daniel Rodríguez-Zúñiga1, Belén Rivaya2, María Vanessa López-Peláez3
1Microbiology Department, Jove Hospital Foundation, Asturias, Gijón, Spain.
Case reports in infectious diseases
|February 23, 2026
Resumen
Blastocystis, un microbio intestinal común, se encontró en un absceso hepático, lo que sugiere que puede diseminarse fuera del intestino. Este caso destaca a Blastocystis como un patógeno oportunista potencial en infecciones extraintestinales.
Área de la Ciencia:
- Microbiología; Enfermedades Infecciosas; Gastroenterología
Sus antecedentes:
- Blastocystis es un protista anaeróbico intestinal común con patogenicidad debatida.
- La diseminación extraintestinal de Blastocystis se reporta raramente, con mecanismos poco claros.
Objetivo del estudio:
- Investigar el potencial de Blastocystis para causar infecciones extraintestinales.
- Identificar los agentes causales de un absceso hepático en una mujer peruana.
Principales métodos:
- Se utilizaron espectrometría de masas, PCR, secuenciación Sanger y métodos basados en cultivo.
- Las muestras incluyeron sangre, tejido (absceso hepático) y materia fecal.
- Técnicas convencionales y moleculares identificaron bacterias aerobias y anaerobias y Blastocystis.
Principales resultados:
- Se identificó Blastocystis subtipo ST1 en el líquido del absceso hepático y se cultivó in vitro.
- También se detectaron bacterias asociadas al intestino, incluyendo Escherichia coli, Eikenella corrodens y Bacteroides fragilis.
- Los hallazgos sugieren que la translocación de la microbiota intestinal a la circulación portal causó la infección.
Conclusiones:
- Blastocystis puede translocarse desde el intestino y actuar como un patógeno oportunista.
- Este caso demuestra que Blastocystis ST1 causa una infección extraintestinal (absceso hepático).
- La translocación de la microbiota intestinal es un mecanismo plausible para tales infecciones invasivas.
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