Jove
Visualize
Contáctanos
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Videos de Conceptos Relacionados

Phase II Reactions: Miscellaneous Conjugation Reactions01:19

Phase II Reactions: Miscellaneous Conjugation Reactions

406
Phase II biotransformations are detoxification mechanisms that conjugate xenobiotics with endogenous substances, neutralizing their toxicity.
A key example involves the conjugation of cyanide ions, which impair cellular respiration and alter hemoglobin into non-oxygen-carrying cyanmethemoglobin. To neutralize this threat, a sulfur atom from thiosulphate is transferred to the cyanide ion, catalyzed by the enzyme rhodanese, resulting in an inactive compound called thiocyanate. The production of...
406
Drug Metabolism: Phase II Reactions01:14

Drug Metabolism: Phase II Reactions

5.3K
Phase II reactions are essential for the detoxification and elimination of drugs from the body. These reactions involve the conjugation of parent drugs or their phase I metabolites with endogenous molecules, resulting in more hydrophilic drug conjugates. The primary conjugation reactions in this phase are sulfation and glucuronidation. Both sulfation and glucuronidation typically produce biologically inactive metabolites. However, in some cases involving prodrugs, active metabolites may be...
5.3K
Photoluminescence: Applications01:14

Photoluminescence: Applications

1.1K
Photoluminescence offers a wide range of applications due to its inherent sensitivity and selectivity. This technique allows for both direct and indirect analyses of the analyte. Direct quantitative analysis is possible when the analyte exhibits a favorable quantum yield for fluorescence or phosphorescence. However, an indirect analysis may be feasible if the analyte is not fluorescent or phosphorescent, or if the quantum yield is unfavorable. Indirect methods include reacting the analyte with...
1.1K
Carbocations02:10

Carbocations

14.0K
Carbocations are one of the reaction intermediates formed during several nucleophilic substitutions or elimination reactions. A carbocation is an electron-deficient species with the central carbon atom having six electrons and three bonded atoms. The central carbon in a carbocation is sp2 hybridized with trigonal planar geometry. It has an empty p orbital perpendicular to the plane of the structure that can accept electrons. Thus, carbocations act as strong electrophiles and may react with any...
14.0K
Allosteric Proteins-ATCase01:19

Allosteric Proteins-ATCase

6.7K
Binding sites linkages can regulate a protein's function.  For example, enzyme activity is often regulated through a feedback mechanism where the end product of the biochemical process serves as an inhibitor.
Aspartate transcarbamoylase (ATCase) is a cytosolic enzyme that catalyzes the condensation of L-aspartate and carbamoyl phosphate to  N-carbamoyl-L-aspartate. This reaction is the first step in pyrimidine biosynthesis. UTP and CTP, the end products of the pyrimidine synthesis...
6.7K
Valence Bond Theory02:42

Valence Bond Theory

11.4K
Coordination compounds and complexes exhibit different colors, geometries, and magnetic behavior, depending on the metal atom/ion and ligands from which they are composed. In an attempt to explain the bonding and structure of coordination complexes, Linus Pauling proposed the valence bond theory, or VBT, using the concepts of hybridization and the overlapping of the atomic orbitals. According to VBT, the central metal atom or ion (Lewis acid) hybridizes to provide empty orbitals of suitable...
11.4K

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

Cyclometallation across metal-carbon bonds; <i>exo</i>-metallated metallacyclopentadiene synthesis.

Dalton transactions (Cambridge, England : 2003)·2026
Same author

Pnictogen-functionalised isocyanide ligands.

Dalton transactions (Cambridge, England : 2003)·2025
Same author

Alkynyltellurolato ligands including a solvatochromic rhenium(I) complex.

Chemical communications (Cambridge, England)·2025
Same author

The Interplay of Methylidyne and Carbido Species: Modeling a Fundamental Step in the Fischer-Tropsch Synthesis.

Angewandte Chemie (International ed. in English)·2025
Same author

Electrophilic As-functionalisation of σ-arsolido complexes.

Dalton transactions (Cambridge, England : 2003)·2024
Same author

σ-Arsolido complexes.

Dalton transactions (Cambridge, England : 2003)·2024

Video Experimental Relacionado

Updated: Feb 24, 2026

Preparation and Use of Carbonyl-decorated Carbenes in the Activation of White Phosphorus
14:07

Preparation and Use of Carbonyl-decorated Carbenes in the Activation of White Phosphorus

Published on: October 3, 2014

14.2K

Dos enfoques para complejos de fosfaniminocarbino

Lucas G Foglia1, Ryan M Kirk1, Anthony F Hill1

  • 1Research School of Chemistry, Australian National University, Canberra, Australian Capital Territory, ACT 2601, Australia. a.hill@anu.edu.au.

Dalton transactions (Cambridge, England : 2003)
|February 23, 2026
PubMed
Resumen
Este resumen es generado por máquina.

Se sintetizaron los primeros complejos de tungsteno fosfaniminocarbino. Estos compuestos novedosos presentan un enlace C-N-P angular, a diferencia de los iminocarbinos lineales.

Palabras clave:
química organometálicaquímica inorgánicacomplejos de tungstenoligandos carbinosfosfaniminocarbino

Más Videos Relacionados

Isolating Free Carbenes, their Mixed Dimers and Organic Radicals
10:44

Isolating Free Carbenes, their Mixed Dimers and Organic Radicals

Published on: April 19, 2019

11.7K
Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions
07:12

Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions

Published on: July 17, 2020

6.7K

Videos de Experimentos Relacionados

Last Updated: Feb 24, 2026

Preparation and Use of Carbonyl-decorated Carbenes in the Activation of White Phosphorus
14:07

Preparation and Use of Carbonyl-decorated Carbenes in the Activation of White Phosphorus

Published on: October 3, 2014

14.2K
Isolating Free Carbenes, their Mixed Dimers and Organic Radicals
10:44

Isolating Free Carbenes, their Mixed Dimers and Organic Radicals

Published on: April 19, 2019

11.7K
Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions
07:12

Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions

Published on: July 17, 2020

6.7K

Área de la Ciencia:

  • Química Organometálica
  • Química Inorgánica

Sus antecedentes:

  • Los complejos de tungsteno son cruciales en catálisis y ciencia de materiales.
  • Los ligandos iminocarbino ofrecen propiedades electrónicas y estéricas únicas.

Objetivo del estudio:

  • Sintetizar y caracterizar novedosos complejos de tungsteno fosfaniminocarbino.
  • Investigar las propiedades estructurales y electrónicas del enlace C-N-P.

Principales métodos:

  • Reacción de un complejo de tungsteno fluorocarbino con un reactivo de fosfina de sililo.
  • Reacción de un complejo de cianuro de tungsteno con un reactivo de haluro de fósforo.
  • Caracterización espectroscópica y estructural de los complejos resultantes.

Principales resultados:

  • Síntesis exitosa de dos nuevos complejos de tungsteno fosfaniminocarbino: [W(CNPPh3)(CO)2(Tp*)] y trans-[W(CNPPh3)Br(CO)4].
  • Se encontró que el enlace C-N-P en [W(CNPPh3)(CO)2(Tp*)] es angular, a diferencia de los iminocarbinos lineales.
  • El átomo de nitrógeno en el enlace angular exhibió una nucleofilicidad insignificante.

Conclusiones:

  • El estudio reporta la primera síntesis de complejos de tungsteno fosfaniminocarbino.
  • La geometría angular del enlace C-N-P representa un nuevo motivo estructural en la química organometálica.
  • Estos hallazgos amplían el alcance de las estructuras de ligandos carbinos conocidos y sus propiedades.