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Updated: Feb 24, 2026
Control of Cell Adhesion using Hydrogel Patterning Techniques for Applications in Traction Force Microscopy
Published on: January 29, 2022
Programación de la fotoelasticidad de hidrogeles para la mecanosensación sin marcadores mediante un lector simultáneo
Riku Katsuki1, Marc Eisenmann2, Shalika Singh3
1Department of Engineering Science, The Graduate School of Informatics and Engineering, The University of Electro-Communications (UEC), 1-5-1 Chofugaoka, Chofu, Tokyo 182-8585, Japan. taki@pc.uec.ac.jp.
Abstract:
We present a strategy to program hydrogel photoelasticity using rationally designed force-transducing crosslinkers. Enabled by a simultaneous birefringence-stress reader (SiBRe), we show that stress-induced unfolding of flexible linkers can amplify the optical response, establishing a robust, dye-free platform for quantitative mechanosensing.
