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Updated: Feb 25, 2026

Detection of a Circulating MicroRNA Custom Panel in Patients with Metastatic Colorectal Cancer
Published on: March 14, 2019
Avances en el estudio de los ARN pequeños nucleolares en el cáncer colorrectal
Ziwen Yuan1, Yafang Chen1, Sicong Liu1
1Department of Laboratory Medicine, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, Jiangsu, China.
Abstract:
Colorectal cancer (CRC) is an important public health challenge worldwide, which has led to a continuous search for more precise diagnostic strategies. Recent studies have revealed that small nucleolar RNAs (snoRNAs) play an important role in CRC. In this article, we first summarize the molecular characteristics and physiological functions of snoRNAs, and then we discuss their mechanisms of action in colorectal carcinogenesis. A key focus is on the emerging potential of snoRNAs as liquid biopsy biomarkers and their prospects for clinical translation in cancer management.
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