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Colágeno de Fuentes Marinas para Aplicación Potencial en el Tratamiento de Heridas
Eleonora Tassara1, Marco Giovine2, Marina Pozzolini3
1Department of Earth, Environment and Life Sciences, University of Genoa, Genoa, Italy.
Progress in molecular and subcellular biology
|February 24, 2026
Resumen
El colágeno marino ofrece una alternativa sostenible a las fuentes terrestres para la medicina regenerativa. Sus diversas propiedades de diversos organismos marinos prometen aplicaciones avanzadas en la cicatrización de heridas.
Área de la Ciencia:
- Ciencia de Biomateriales
- Medicina Regenerativa
- Biotecnología Marina
Sus antecedentes:
- El colágeno, una proteína clave de la matriz extracelular, es vital para la regeneración de tejidos.
- Las preocupaciones éticas y de seguridad asociadas con el colágeno terrestre impulsan la búsqueda de alternativas.
- Los ecosistemas marinos proporcionan una fuente rica y sostenible de diversos tipos de colágeno.
Objetivo del estudio:
- Explorar las aplicaciones del colágeno derivado del mar en la cicatrización de heridas.
- Comparar los rasgos bioquímicos y estructurales del colágeno marino con el colágeno terrestre.
- Revisar los usos innovadores del colágeno marino en biomateriales para la reparación de la piel.
Principales métodos:
- Revisión de literatura sobre fuentes y propiedades del colágeno marino.
- Análisis de la diversidad del colágeno en filos marinos (vertebrados e invertebrados).
- Examen de las aplicaciones del colágeno marino en andamios, películas y péptidos.
Principales resultados:
- El colágeno marino exhibe una diversidad significativa en estructura y propiedades.
- El colágeno de pescado, aunque abundante, puede tener una menor estabilidad térmica.
- Ciertos colágenos de invertebrados (p. ej., esponjas, moluscos) muestran características mecánicas y térmicas únicas.
- El colágeno y la gelatina marinos se utilizan en biomateriales innovadores para la reparación de heridas.
Conclusiones:
- El colágeno marino es un biomaterial prometedor y sostenible para la medicina regenerativa y la cicatrización de heridas.
- La biodiversidad marina ofrece un potencial sin explotar para el desarrollo de biomateriales novedosos.
- Una mayor investigación sobre el colágeno marino puede conducir a soluciones terapéuticas más eficientes y ecológicas.
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