Jove
Visualize
Contáctanos
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Videos de Conceptos Relacionados

Fungal Group Zygomycota01:29

Fungal Group Zygomycota

1.6K
Zygomycota, previously classified as a distinct fungal group, are primarily terrestrial, saprophytic molds that play a crucial role as decomposers. Recent phylogenetic studies have revealed that these fungi are now divided into two major clades — Mucoromycota, which includes many symbiotic species, and Zoopagomycota, which primarily consists of parasitic and pathogenic fungi. These groups exhibit distinct ecological roles and reproductive strategies while sharing key structural and...
1.6K
The Roles of Bacteria and Fungi in Plant Nutrition02:11

The Roles of Bacteria and Fungi in Plant Nutrition

47.5K
Plants have the impressive ability to create their own food through photosynthesis. However, plants often require assistance from organisms in the soil to acquire the nutrients they need to function correctly. Both bacteria and fungi have evolved symbiotic relationships with plants that help the species to thrive in a wide variety of environments.
47.5K
Overview of Fungi01:29

Overview of Fungi

2.1K
Fungi are a diverse group of eukaryotes more closely related to animals than other eukaryotes. Fungal cell walls comprise chitin, a polysaccharide that provides structural strength, and glucans, which contribute to flexibility and integrity. Other polysaccharides, such as mannans and galactosans, may supplement or replace chitin in some fungi. These adaptations, along with their preference for acidic environments and tolerance for high osmotic pressure, enable fungi to thrive in various...
2.1K
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

606
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
606
Bacterial Flora of the Large Intestine01:29

Bacterial Flora of the Large Intestine

1.8K
The gut microbiome is formed by a vast and diverse community of bacteria that colonizes our large intestine. These bacteria start residing in the gut from birth and continue diversifying throughout life, influenced by factors such as diet, lifestyle, and stress. The gut bacterial community also includes bacteria from food and those that enter the colon through the anus.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
1.8K
Defense Mechanism Against Infection01:26

Defense Mechanism Against Infection

10.0K
Natural flora, body system defenses, and inflammation are natural barriers of the body against infectious agents regardless of previous exposure. Normal floras of the human body refer to the microbial population that colonizes the skin and mucous membranes.
In addition, many body organ systems have unique defenses against infection. The skin is an intact, multilayered surface preventing invasion by microorganisms unless impaired. Mucous membranes lining the mouth, nose, and eyelids are barriers...
10.0K

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

Self-sustained heterogeneity drives PDAC.

Science signaling·2026
Same author

An inflammation memento.

Science signaling·2026
Same author

<i>Shigella</i> mixes and matches host proteins.

Science signaling·2025
Same author

Sensory support for stem cells.

Science signaling·2025
Same author

Estrogen-powered kidney protection.

Science signaling·2025
Same author

GAGging cancer cell ferroptosis.

Science signaling·2025

Video Experimental Relacionado

Updated: Feb 26, 2026

Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model
05:41

Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model

Published on: April 6, 2022

3.5K

Los hongos facilitan la curación intestinal

Annalisa M VanHook1

  • 1Science Signaling, AAAS, Washington, DC 20005, USA.

Science signaling
|February 24, 2026
PubMed
Resumen

Una proteína de un hongo de ratón ayuda a curar el intestino. Este descubrimiento ofrece nuevas formas de tratar el daño intestinal.

Área de la Ciencia:

  • Microbiología
  • Gastroenterología
  • Inmunología

Sus antecedentes:

  • La integridad de la barrera intestinal es crucial para la salud.
  • La disfunción de la barrera intestinal está implicada en diversas enfermedades gastrointestinales.
  • Los microorganismos comensales desempeñan un papel en el mantenimiento de la homeostasis intestinal.

Objetivo del estudio:

  • Investigar el papel de las proteínas secretadas por los hongos comensales en la reparación intestinal.
  • Identificar proteínas fúngicas específicas que promuevan la curación del revestimiento intestinal.

Principales métodos:

  • Se utilizaron modelos de ratones para estudiar la reparación intestinal.
  • Se aisló y caracterizó una proteína específica secretada por un hongo comensal de ratón.
Palabras clave:
Malassezia globosareparación intestinalproteínas fúngicasmicrobioma intestinalenfermedades inflamatorias intestinales

Más Videos Relacionados

Microfluidic Tools for Probing Fungal-Microbial Interactions at the Cellular Level
08:19

Microfluidic Tools for Probing Fungal-Microbial Interactions at the Cellular Level

Published on: June 23, 2022

4.3K
An Intestinal Gut Organ Culture System for Analyzing Host-Microbiota Interactions
05:27

An Intestinal Gut Organ Culture System for Analyzing Host-Microbiota Interactions

Published on: June 30, 2021

5.2K

Videos de Experimentos Relacionados

Last Updated: Feb 26, 2026

Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model
05:41

Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model

Published on: April 6, 2022

3.5K
Microfluidic Tools for Probing Fungal-Microbial Interactions at the Cellular Level
08:19

Microfluidic Tools for Probing Fungal-Microbial Interactions at the Cellular Level

Published on: June 23, 2022

4.3K
An Intestinal Gut Organ Culture System for Analyzing Host-Microbiota Interactions
05:27

An Intestinal Gut Organ Culture System for Analyzing Host-Microbiota Interactions

Published on: June 30, 2021

5.2K
  • Se evaluó el efecto de esta proteína sobre las células epiteliales intestinales in vitro e in vivo.

    • Principales resultados:

    • Se identificó una proteína secretada por el hongo comensal de ratón *Malassezia globosa*.
    • Esta proteína aceleró significativamente la reparación del daño intestinal inducido químicamente en ratones.
    • La proteína demostró la capacidad de promover la proliferación y migración de las células epiteliales intestinales.

    Conclusiones:

    • Una proteína fúngica puede estimular la reparación intestinal, lo que pone de relieve una nueva diana terapéutica.
    • Este hallazgo abre nuevas vías para el desarrollo de tratamientos para las enfermedades inflamatorias intestinales y otros trastornos gastrointestinales.
    • El estudio subraya la compleja interacción entre los hongos comensales y la salud intestinal del huésped.