Video Experimental Relacionado

Updated: Feb 26, 2026

Assessment of Global Ocular Structure Following Spaceflight Using a Micro-Computed Tomography Micro-CT Imaging Method

Assessment of Global Ocular Structure Following Spaceflight Using a Micro-Computed Tomography Micro-CT Imaging Method

Published on: October 27, 2020

Impacto de los factores estresantes del vuelo espacial en la función mitocondrial y el riesgo de desarrollo de

Daniel P LeBlanc¹, Brian Butterfield², Luis Jimenez-Chavez³

¹The University of Texas Medical Branch, Galveston, TX, USA. dpleblan@utmb.edu.

NPJ microgravity

|February 24, 2026

Abstract:

Spaceflight stressors such as microgravity and radiation disrupt mitochondria in ocular tissues, leading to impaired energy production, oxidative stress, and reduced repair capacity. The anatomical distribution of mitochondria and disease localization presents an interesting relationship: cortical lens mitochondria align with the type of cataracts seen in spaceflight, while retinal mitochondria correspond to the pathology of SANS. These observations suggest mitochondrial damage may be more central to spaceflight-associated pathologies than previously recognized.

Palabras clave:

vuelo espacial estresores mitocondrias función mitocondrial patología ocular cataratas SANS microgravedad radiación

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