Video Experimental Relacionado
Updated: Feb 26, 2026

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA
Published on: April 24, 2017
Variante Anatómica o Anomalía Patológica? Un Informe de Caso de un Fenómeno Aislado Asintomático del Ápice Cardíaco
Charles Malisaba Posite1,2,3, Abdul Katongole4, Mahad Said Mohamed1
1Department of Pathology, Kampala International University, Ishaka, Uganda.
Background:
Congenital cardiac malformations are the most common birth defects, with a global prevalence of approximately 8 per 1000 live births. While most are symptomatic, a small subset of structural variants can remain clinically silent. We report a rare case of a deep apical cleft, an incidental and benign post-mortem finding that must be differentiated from clinically significant pathologies such as left ventricular non-compaction cardiomyopathy, ventricular diverticula, or aneurysms.
Case Presentation:
During an autopsy of a 38-year-old African male, deceased from a road traffic accident, a deep, V-shaped cleft was discovered at the anterior cardiac apex, measuring 4.2 cm in length and 1.5 cm in depth. The heart was otherwise grossly normal, with no evidence of hypertrophy, septal defects, or vascular anomalies. The patient had no prior history of cardiac symptoms.
Conclusion:
The isolated cardiac apical cleft in this asymptomatic adult is a rare anatomical variant, likely a benign developmental anomaly. This case highlights the critical importance of meticulous post-mortem examination and anatomical knowledge to distinguish between a harmless congenital variant and a pathological condition, serving as a valuable educational case for forensic pathologists and cardiac specialists.
Videos de Conceptos Relacionados
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Aneurysm I: Introduction
Cardiovascular System Abnormal Findings II: Auscultation
Abnormal Heart Sounds
Gallops:
Cardiomyopathy I: Introduction and Classification
Mitral Stenosis II: Clinical features and Diagnostic Tests
Aortic Regurgitation II: Clinical Features and Diagnostic Tests

