Video Experimental Relacionado

Updated: Feb 26, 2026

Quantitative Measurement of Intrathecally Synthesized Proteins in Mice
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Quantitative Measurement of Intrathecally Synthesized Proteins in Mice

Published on: November 29, 2019

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Deterioro de la depuración de proteínas del LCR revelado mediante cinética de isótopos estables en la hidrocefalia de

Claire A Leckey1,2, Tatiana A Giovannucci1,2, Eimear C Murphy1

  • 1Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.

Brain communications
|February 25, 2026
PubMed
Resumen

La hidrocefalia de presión normal (HPN) presenta una depuración alterada de proteínas del líquido cefalorraquídeo (LCR). Un nuevo método de marcaje con isótopos estables revela una depuración significativamente más lenta de la transtirretina en pacientes con HPN, lo que sugiere una nueva herramienta de diagnóstico y monitorización para el flujo del LCR.

Palabras clave:
cognitivodemencianeurocirugía

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