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Moduladores de la FQTR y Variantes Raras: ¿Del Laboratorio a la Efectividad en el Mundo Real?

Nicholas J Simmonds1,2, Damian G Downey3

  • 1Adult Cystic Fibrosis Centre, Royal Brompton Hospital, part of Guy's and St Thomas's NHS Foundation Trust, London, United Kingdom.

American journal of respiratory and critical care medicine
|February 25, 2026
PubMed
Resumen

No abstract available in PubMed .

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Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...
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