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Creating Sub-50 Nm Nanofluidic Junctions in PDMS Microfluidic Chip via Self-Assembly Process of Colloidal Particles
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Microfluídica 2.5D replicable de PDMS con características nanométricas de precisión amplía las dimensiones de los
1Department of Earth and Environmental Engineering, Columbia University, New York, USA. sak2280@columbia.edu.
Soft matter
|February 25, 2026
Abstract:
Customizable 2.5D microfluidic chips, tailored for rock-on-a-chip studies, are developed using direct laser writing (DLW) and soft lithography. Chip microchannels feature varied cross-sectional shape and height, convergences as small as 1-2 µm, and controlled nanoscale surface roughness. The impact of these 2.5D features on pore-scale transport phenomena is demonstrated with trapped bubble dissolution experiments.
