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Optogenetic Perturbation of Neural Activity with Laser Illumination in Semi-intact Drosophila Larvae in Motion
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ShineGAL4 drivers para optogenética específica de tejido y tipo celular en Drosophila
Victor Girard1, Sebastian Sorge1, Joachim Kurth1
1The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
Development (Cambridge, England)
|February 25, 2026
Resumen
Los investigadores desarrollaron ShineGAL4, un sistema optogenético para la manipulación genética precisa en Drosophila. Esta herramienta permite la expresión génica inducida por luz en diversos tejidos y tipos celulares con un control espaciotemporal preciso.
Conclusiones:
- El sistema ShineGAL4 proporciona una precisión espaciotemporal sin precedentes para la manipulación genética en Drosophila.
- Este nuevo panel de herramientas optogenéticas amplía las posibilidades para estudiar la función génica en diversos tejidos y tipos celulares.
- ShineGAL4 facilita un control preciso sobre la expresión génica, avanzando la investigación en Drosophila.
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