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Updated: Feb 26, 2026

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance
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Vínculos específicos de los síntomas entre problemas internalizantes y conectividad funcional en adolescentes: un

Valerie Karl1, Ludvig D Bjørndal2,3, Eira R Aksnes2,4

  • 1PROMENTA Research Center, Department of Psychology, University of Oslo, Blindern, PO Box 1094, 0317, Oslo, Norway. valerie.karl@psykologi.uio.no.

European child & adolescent psychiatry
|February 25, 2026
PubMed
Resumen

Los problemas internalizantes en adolescentes están relacionados con la conectividad de redes cerebrales específicas. Los sentimientos de inutilidad, culpa, tristeza y miedo muestran asociaciones distintas con las redes de control de la saliencia, frontoparietal y por defecto.

Palabras clave:
ABCDConectividad funcionalProblemas internalizantesAnálisis de redesRedes de síntomasJuventud

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Área de la Ciencia:

  • Neurociencia
  • Psicología del Desarrollo
  • Psiquiatría Infantil

Sus antecedentes:

  • Los problemas internalizantes en los jóvenes son comunes pero heterogéneos.
  • Investigaciones previas relacionaron los problemas internalizantes con las redes cerebrales de control de la saliencia (SA), frontoparietal (FP) y por defecto (DN).
  • Comprender la conectividad cerebral específica de los síntomas es crucial debido a la comorbilidad.

Objetivo del estudio:

  • Investigar las asociaciones específicas de los síntomas entre los problemas internalizantes y la conectividad funcional cerebral en adolescentes.
  • Explorar las diferencias específicas de sexo y momento en estos vínculos.

Principales métodos:

  • Se utilizó una gran muestra poblacional de adolescentes (N=2426).
  • Se empleó un enfoque integrado de modelado de redes.
  • Se analizaron los síntomas internalizantes autoinformados y los datos de conectividad funcional.

Principales resultados:

  • Se encontraron asociaciones negativas entre la inutilidad/culpa y la conectividad dentro de la red de control de la saliencia (DN).
  • Se encontraron asociaciones positivas entre el miedo y la conectividad dentro de la red frontoparietal (FP).
  • La tristeza y el miedo se asociaron positivamente con la conectividad entre redes de la red de control de la saliencia (DN-SA).

Conclusiones:

  • Los problemas internalizantes en los jóvenes se asocian con patrones específicos de la circuitería funcional cerebral.
  • Los hallazgos resaltan una compleja interacción entre los síntomas internalizantes y las redes cerebrales.
  • La conectividad cerebral temprana puede predecir síntomas internalizantes posteriores.