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Updated: Feb 28, 2026

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Primeros inhibidores covalentes selectivos de FGFR3: superando la toxicidad y la resistencia

Liang Ouyang1

  • 1State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, and Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu 610041, China.

Journal of medicinal chemistry
|February 27, 2026
PubMed
Resumen

El primer inhibidor selectivo covalente de FGFR3 ofrece una solución prometedora para los cánceres alterados por FGFR3, superando los problemas de toxicidad y resistencia comunes con los inhibidores de pan-FGFR en la terapia dirigida.

Palabras clave:
inhibidores covalentesFGFR3terapia dirigidacáncerresistenciatoxicidad

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