Video Experimental Relacionado
Updated: May 27, 2026
10:15
Utilizing Repetitive Transcranial Magnetic Stimulation to Improve Language Function in Stroke Patients with Chronic Non-fluent Aphasia
Published on: July 2, 2013
18.4K
Interferencia temporal personalizada dirigida al estriado derecho mejora los acoplamientos estructura-función en la
Dongsheng Tang1, Lang Qin1, Wenhua Liu1
1School of Kinesiology, Shenzhen University, No. 3688 Nanhai Avenue, Nanshan District, Shenzhen, Guangdong 518060, China.
Cerebral cortex (New York, N.Y. : 1991)
|February 28, 2026
Resumen
La estimulación personalizada por interferencia temporal (TI) alteró de forma segura la conectividad y la estructura cerebral en adultos sanos. Esta neuromodulación de la red córtico-estriado-talámica-cortical muestra una gran promesa para el tratamiento de trastornos neuropsiquiátricos.
Área de la Ciencia:
- Neurociencia
- Neuromodulación
- Neuroimagen
Sus antecedentes:
- La red córtico-estriado-talámica-cortical (CSTC) es crucial para el control motor y el procesamiento de recompensas.
- La disfunción en la red CSTC está implicada en varios trastornos neuropsiquiátricos.
- Se necesitan técnicas de neuromodulación no invasivas para investigar y tratar potencialmente las condiciones relacionadas con CSTC.
Objetivo del estudio:
- Investigar los efectos neuromoduladores de la estimulación personalizada por interferencia temporal (TI) en la plasticidad funcional-estructural dentro de la red CSTC.
- Evaluar el impacto de la estimulación TI en la conectividad funcional (FC) y la microestructura de la materia blanca.
- Evaluar la seguridad y tolerabilidad de la estimulación TI personalizada.
Principales métodos:
- 26 participantes sanos recibieron estimulación TI personalizada y simulada dirigida al estriado derecho.
- Se adquirieron imágenes de resonancia magnética funcional (fMRI) y imágenes de tensor de difusión (DTI) antes, durante y después de la estimulación.
- El análisis se centró en los cambios en la FC dentro de la red CSTC y las métricas de difusión (difusividad axial (AD), anisotropía fraccional (FA)) en los tractos de materia blanca.
Principales resultados:
- La estimulación TI redujo significativamente la conectividad funcional (FC) entre el estriado derecho y el giro precentral.
- Se observaron aumentos agudos en la difusividad axial (AD) en el tracto corticoespinal derecho (CST) y la radiación talámica anterior (ATR) durante la estimulación.
- Se observó una elevación retardada en la anisotropía fraccional (FA) en la ATR derecha después de la estimulación, con una correlación negativa entre la FC y los cambios en la AD.
- No se informaron efectos adversos, lo que confirma la seguridad del procedimiento.
Conclusiones:
- La estimulación TI personalizada modula eficazmente la conectividad funcional e induce cambios neuroplásticos dentro de la red CSTC.
- Las alteraciones funcionales y microestructurales observadas sugieren el potencial de la TI para aplicaciones terapéuticas.
- La estimulación TI representa una estrategia neuromoduladora prometedora, segura y eficaz para los trastornos neuropsiquiátricos.
Palabras clave:
red córtico-estriado-talámica-cortical (cstc)conectividad funcionalestimulación cerebral personalizadaacoplamiento estructura-funciónestimulación por interferencia temporalMás Videos Relacionados
09:26Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication
Published on: February 6, 2019
22.3K
13:20Online Repetitive Transcranial Magnetic Stimulation of Dorsomedial and Dorsolateral Prefrontal Cortex in Cognition Decision Making, and Cognitive Dissonance
Published on: December 5, 2025
1.1K
Videos de Conceptos Relacionados
02:18Interference and Diffraction
Interference is a characteristic phenomenon exhibited by waves. When two electromagnetic waves interact with their peaks and troughs coinciding, a resulting wave with enhanced amplitude is produced. This is known as constructive interference. In this case, the two waves interacting are in phase with each other.
01:07Interference and Superposition of Waves
When two waves of the same nature occur in the same region simultaneously, they result in interference. Interference of waves implies that the net effect of the waves is the sum of the individual waves' effects. However, it does not imply that the individual waves affect the propagation of other waves.
Interference occurs in mechanical waves, such as sound waves, waves on a string, and surface water waves. Mechanical waves correspond to the physical displacement of particles. Hence,...
Interference occurs in mechanical waves, such as sound waves, waves on a string, and surface water waves. Mechanical waves correspond to the physical displacement of particles. Hence,...
01:10Interference: Path Lengths
Consider two sources of sound, that may or may not be in phase, emitting waves at a single frequency, and consider the frequencies to be the same.
Two special sources may be considered when they are in phase. This can be easily achieved by feeding the two sources from the same source. An example would be synchronizing the two speakers by feeding them with the same source, such as the sound waves produced by a tuning fork. This setup ensures that the two sources have the same frequency and are...
Two special sources may be considered when they are in phase. This can be easily achieved by feeding the two sources from the same source. An example would be synchronizing the two speakers by feeding them with the same source, such as the sound waves produced by a tuning fork. This setup ensures that the two sources have the same frequency and are...
01:10Deformation in a Circular Shaft
One of the distinctive characteristics of circular shafts is their ability to maintain their cross-sectional integrity under torsion. In other words, each cross-section continues to exist as a flat, unaltered entity, simply rotating like a solid, rigid slab. To understand the distribution of shearing stress within such a shaft, consider a cylindrical section inside this circular shaft. This section has a length of L and a radius of R, with one end fixed. The radius of the cylindrical section is...
01:21Deformations in a Transverse Cross Section
When a material is subjected to uniaxial stress, it elongates or contracts in the direction of the applied force, and also undergoes changes in the perpendicular directions. This behavior is crucial for understanding how materials behave under stress and is governed by mechanical properties such as Poisson's ratio v, which measures the ratio of transverse strain to axial strain.
As the material stretches, it expands or contracts in orthogonal directions to the load. This phenomenon varies...
As the material stretches, it expands or contracts in orthogonal directions to the load. This phenomenon varies...
01:20Elastic Strain Energy for Shearing Stresses
As discussed in previous lessons, strain energy in a material is the energy stored when it is elastically deformed, a concept crucial in materials science and mechanical engineering. This energy results from the internal work done against the cohesive forces within the material. When a material undergoes shearing stress and corresponding shearing strain, the strain energy density, which is the energy stored per unit volume, is calculated. Within the elastic limit, where the stress is...