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Análisis exhaustivo de las anomalías citogenéticas comunes en el mieloma múltiple: de la investigación básica a las

Chenbo Yang¹, Xiaonan Liu¹, Yiwei Li²

¹Department of Pathology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China; Henan Key Laboratory of Tumor Pathology, Zhengzhou University, Zhengzhou, China.

|February 28, 2026

Resumen

Las anomalías citogenéticas en el mieloma múltiple (MM) impactan significativamente el pronóstico. La detección de marcadores genéticos específicos como la deleción de P53 mejora la estratificación del riesgo y guía las estrategias de tratamiento personalizadas para pacientes con MM.

Palabras clave:

deleción 1p32 ganancia/amplificación 1q21 deleción D13S319 translocación IGH Mieloma múltiple deleción P53 deleción RB1

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