Video Experimental Relacionado

Updated: Mar 3, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

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Moléculas quirales mecánicamente planares mediante un enfoque auxiliar de SuFEx

Shengtong Niu1, Yingying Jiang1, Darian W Lewis1

  • 1Department of Chemistry, University of Wyoming, Laramie, Wyoming, USA.

Angewandte Chemie (International ed. in English)
|March 2, 2026
PubMed
Resumen

Este estudio presenta una reacción de clic SuFEx sin metales para la síntesis de rotaxanos quirales mecánicamente planares (MPC) a escala de gramo. Luego se producen eficientemente rotaxanos y catenanos MPC enantiopuros, superando los desafíos sintéticos anteriores.

Palabras clave:
SuFExcatenanosquiralidad mecánicamoléculas mecánicamente entrelazadasrotaxanos

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