Video Experimental Relacionado

Updated: May 5, 2026

A Simple Approach to Induce Experimental Autoimmune Neuritis in C57BL/6 Mice for Functional and Neuropathological Assessments
07:30

A Simple Approach to Induce Experimental Autoimmune Neuritis in C57BL/6 Mice for Functional and Neuropathological Assessments

Published on: November 9, 2017

8.9K

[Comentario sobre el artículo: "Aspectos epidemiológicos y clínicos del síndrome de Guillain-Barré, 2012-2022"]

Diana Gómez-Madrigal1

  • 1Instituto Mexicano del Seguro Social, Hospital General de Zona con Unidad de Medicina Familiar No. 8, Servicio de Neurología. Ciudad de México, México.

Revista medica del Instituto Mexicano del Seguro Social
|March 3, 2026
PubMed

Un subanálisis reveló diferencias significativas entre las variantes del síndrome de Guillain-Barré (SGB). La forma axonal se asoció con antecedentes de infección gastrointestinal y una mayor debilidad muscular (fuerza < 3 en la escala clínica), mientras que la polirradiculoneuropatía desmielinizante inflamatoria aguda (AIDP) se vinculó con mayor frecuencia a infecciones respiratorias previas. Estos hallazgos resaltan el valor clínico de la historia clínica del paciente para sospechar el subtipo axonal, lo cual es relevante para el manejo temprano y el pronóstico del SGB.

Palabras clave:
Enfermedades autoinmunesEnfermedades AutoinmunesSíndrome de Guillain-BarréPolirradiculoneuropatíaPolirradiculoneuropatíaSíndrome de Guillain-Barré

Más Videos Relacionados

In Vivo Electrophysiological Measurement of Compound Muscle Action Potential from the Forelimbs in Mouse Models of Motor Neuron Degeneration06:35

In Vivo Electrophysiological Measurement of Compound Muscle Action Potential from the Forelimbs in Mouse Models of Motor Neuron Degeneration

Published on: June 15, 2018

22.7K
Author Spotlight: Expanding the Scope of Multiplex Immunoassays for Lyme Borreliosis Diagnostics and Pathogen Research05:25

Author Spotlight: Expanding the Scope of Multiplex Immunoassays for Lyme Borreliosis Diagnostics and Pathogen Research

Published on: July 14, 2023

2.5K

Videos de Conceptos Relacionados

Encephalitis ll: Pathophysiology01:26

Encephalitis ll: Pathophysiology

Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...
30
Multiple Sclerosis l: Introduction01:19

Multiple Sclerosis l: Introduction

Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
31
Myasthenia Gravis ll: Pathophysiology01:22

Myasthenia Gravis ll: Pathophysiology

The disease process of myasthenia gravis begins at the neuromuscular junction, where antibodies attack key proteins needed for muscle activation. This immune reaction weakens signal transmission, leading to the characteristic muscle fatigue and weakness that define the condition.Immune-Mediated DamageIn most individuals, antibodies target acetylcholine receptors (AChRs) on the postsynaptic membrane of muscle cells. By blocking acetylcholine binding, these antibodies prevent the nerve signal...
69
Secondary Spinal Cord Injury llI: Pathophysiology01:25

Secondary Spinal Cord Injury llI: Pathophysiology

Early Ischemia and Ionic ImbalanceWithin minutes of spinal cord injury, a secondary cascade begins, progressing over hours to weeks. Vascular damage reduces blood flow, causing ischemia and mitochondrial dysfunction. ATP depletion leads to ion pump failure, membrane depolarization, sodium influx, potassium efflux, and water accumulation, resulting in cellular swelling. Increased intracellular calcium further disrupts mitochondria and accelerates cellular injury.Excitotoxicity and Neuronal...
68