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Enrojecimientos en la menopausia: un vínculo neuroendocrino con la secreción pulsátil de la hormona luteinizante
Science (New York, N.Y.)
|August 24, 1979
Resumen
Los sofocos durante la menopausia están relacionados con la glándula pituitaria.
Área de la Ciencia:
- La neuroendocrinología en neuroendocrinología.
- La Medicina Reproductiva es una de ellas.
- Investigación de la menopausia Investigación de la menopausia.
Sus antecedentes:
- Los sofocos de la menopausia son un síntoma común y perjudicial.
- Los desencadenantes fisiológicos subyacentes para los sofocos siguen siendo incompletamente entendidos.
Objetivo del estudio:
- Para investigar los eventos neuroendocrinos que preceden a los sofocos de la menopausia.
- Para explorar la relación entre la liberación de la hormona luteinizante y el inicio de los sofocos.
Principales métodos:
- Estudio de observación que monitorea los parámetros hormonales y fisiológicos durante los sofocos de la menopausia.
- La medición de la hormona luteinizante, las catecolaminas y los niveles de prolactina.
Principales resultados:
- Los episodios de enrojecimiento en la menopausia coincidieron constantemente con el inicio de la liberación de la hormona luteinizante (LH) pulsátil de la hipófisis.
- No se observaron alteraciones significativas en los niveles circulantes de catecolamina o prolactina durante estos episodios.
Conclusiones:
- Los hallazgos sugieren una relación directa entre el control neuroendocrino de la secreción pulsativa de LH y la aparición de los sofocos de la menopausia.
- La regulación hipotalámica del factor de liberación de la hormona luteinizante puede desempeñar un papel en el desencadenamiento de los episodios de sofocos.
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