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Agammaglobulinemia infantil y hipersensibilidad inmediata a la penicilina G
JAMA
|April 25, 1977
Resumen
La agammaglobulinemia infantil ligada a X (XLA) puede presentarse con niveles normales de inmunoglobulina E (IgE), lo que lleva a reacciones atópicas y alérgicas. La terapia profiláctica con ampicilina redujo las infecciones en un paciente con XLA y IgE normal.
Área de la Ciencia:
- Inmunología Inmunología.
- Alergia pediátrica a las alergias en niños.
- Genética La genética.
Sus antecedentes:
- La agammaglobulinemia infantil ligada a X (XLA) es una inmunodeficiencia primaria caracterizada por una severa reducción de las células B y la mayoría de los isotipos de inmunoglobulina (Ig).
- La síntesis de inmunoglobulina E (IgE) conservada es atípica en XLA, ya que los niveles de IgE son típicamente bajos o indetectables.
- La atopia y la anafilaxia son preocupaciones clínicas significativas, particularmente cuando se considera la terapia con antibióticos.
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