Video Experimental Relacionado

Updated: Jun 2, 2026

In vivo Application of the REMOTE-control System for the Manipulation of Endogenous Gene Expression
08:54

In vivo Application of the REMOTE-control System for the Manipulation of Endogenous Gene Expression

Published on: March 29, 2019

Excisión de un intrón intacto como una nueva estructura lariat durante el splicing pre-mRNA in vitro

B Ruskin, A R Krainer, T Maniatis

    Cell
    |August 1, 1984
    PubMed
    Resumen

    Este estudio revela que el empalme de ARN implica una estructura lariat formada por la primera secuencia intermedia (IVS1) de ARN beta-globina humana. Esta estructura de lariat, con un enlace único de 2-5 fosfodiéster, participa activamente en el mecanismo de empalme.

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