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Updated: Jul 23, 2026

Rapid Quantification of Mitogen-induced Blastogenesis in T Lymphocytes for Identifying Immunomodulatory Drugs
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Published on: December 27, 2016

Los mitógenos aumentan la fosforilación de los fosfoinosítidos en los timocitos

M V Taylor, J C Metcalfe, T R Hesketh

    Nature
    |November 5, 1984
    PubMed
    Resumen

    Las interacciones ligando-receptor desencadenan la descomposición y resíntesis del fosfatidilinositol 4,5-bisfosfato. Los mitógenos como TPA, A23187 y Con A aumentan la fosforilación del fosfatidilinositol en los timocitos de ratón, lo que sugiere una vía de señalización común.

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