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Published on: June 23, 2015
Bacteriuria y posterior mortalidad en mujeres
Lancet (London, England)
|January 16, 1982
Resumen
La bacteriuria, o bacterias en la orina, está relacionada con tasas de mortalidad más altas en las mujeres. Este riesgo aumenta con la bacteriuria persistente, destacando su importancia clínica.
Área de la Ciencia:
- Urología Urología Urología.
- Epidemiología La epidemiología.
- Gerontología Gerontología.
Sus antecedentes:
- La bacteriuria es común en las mujeres y se ha relacionado con varios resultados de salud.
- Comprender el riesgo de mortalidad a largo plazo asociado con la bacteriuria es crucial para la salud pública.
Objetivo del estudio:
- Investigar la asociación entre la bacteriuria y la mortalidad subsiguiente en una cohorte de mujeres basada en la población.
- Para determinar si la bacteriuria persistente confiere un mayor riesgo de mortalidad.
Principales métodos:
- Estudio de cohorte basado en la población que involucra a mujeres en Jamaica y Gales durante un período de 13 años.
- Se llevaron a cabo tres encuestas, con bacteriuria definida como >= 10(5) bacilos gram-negativos / ml en tres cultivos de orina consecutivos durante 3 semanas.
- Los datos de mortalidad se recopilaron en la segunda y tercera encuestas, con análisis ajustados por edad y peso.
Principales resultados:
- La bacteriuria se asoció significativamente con un aumento de la mortalidad tanto en los análisis crudos como en los ajustados.
- Las mujeres bacteriúricas en la primera encuesta tenían un riesgo 1,5 veces mayor de muerte en la tercera encuesta.
- Las mujeres con bacteriuria persistente en las dos primeras encuestas mostraron el mayor índice de riesgo ajustado de muerte (2.0) entre la segunda y la tercera encuestas.
Conclusiones:
- La bacteriuria es un factor de riesgo significativo para la mortalidad posterior en las mujeres.
- La bacteriuria persistente se asocia con un riesgo sustancialmente elevado de muerte.
- Estos hallazgos subrayan la importancia del monitoreo y el manejo de la bacteriuria en las mujeres, particularmente en las poblaciones mayores.
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