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La deficiencia de proteínas, la deficiencia de energía y el edema de la desnutrición
Lancet (London, England)
|June 5, 1982
Resumen
La ingesta de energía dietética, no de proteínas, tiene un impacto significativo en la pérdida de edema en niños desnutridos. La resolución del edema requiere energía adecuada, lo que sugiere que otros factores como el potasio pueden estar involucrados en el kwashiorkor.
Área de la Ciencia:
- Bioquímica nutricional y nutrición.
- Desnutrición pediátrica La desnutrición pediátrica es la desnutrición de los niños.
Sus antecedentes:
- La causa exacta del kwashiorkor, una forma de desnutrición, sigue siendo objeto de debate.
- La deficiencia de proteínas en la dieta a menudo está implicada, pero su papel en el edema kwashiorkor es incierto.
Objetivo del estudio:
- Investigar la relación entre la ingesta dietética y la resolución del edema en niños con desnutrición.
- Para determinar si la ingesta de proteínas o energía es el principal impulsor de la pérdida de edema.
Principales métodos:
- Un estudio en el que participaron 103 niños con desnutrición edematosa.
- Se administraron seis dietas terapéuticas diferentes.
- El análisis de correlación se utilizó para evaluar el impacto de la ingesta de energía y proteínas en la pérdida de edema.
Principales resultados:
- La tasa de pérdida de edema se correlacionó fuertemente con la ingesta de energía dietética (r = 0.75), no con la ingesta de proteínas (r = 0.03).
- Los niños con dietas muy bajas en proteínas perdieron el edema tan rápidamente como aquellos con dietas más altas en proteínas.
- Se identificó una ingesta de energía de 245-270 KJ / kg / día como el umbral para la resolución del edema.
Conclusiones:
- Es poco probable que la deficiencia de proteínas en la dieta sea la causa principal del edema de kwashiorkor.
- La deficiencia de energía por sí sola no explica la acumulación de edema.
- El potasio y otros factores pueden desempeñar un papel, lo que sugiere una patogénesis similar al edema por inanición.
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