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Un ensayo aleatorizado, doble ciego y cruzado de potasio en la presión arterial en sujetos normales
Lancet (London, England)
|November 20, 1982
Resumen
El aumento de la ingesta oral de potasio redujo significativamente la presión arterial en hombres sanos. La suplementación redujo la presión diastólica media en 2,4 mm Hg, destacando el potasio.
Área de la Ciencia:
- Salud cardiovascular La salud cardiovascular es la salud cardiovascular.
- Nutrición Humana La nutrición humana es la nutrición de las personas.
- Los ensayos clínicos son ensayos clínicos.
Sus antecedentes:
- La presión arterial elevada es un factor de riesgo importante para las enfermedades cardiovasculares.
- El equilibrio mineral de la dieta, particularmente el sodio y el potasio, influye en la regulación de la presión arterial.
- El papel de la suplementación de potasio en individuos normotensos requiere más investigación.
Objetivo del estudio:
- Para evaluar el efecto del aumento de la ingesta oral de potasio en la presión arterial en hombres jóvenes y sanos.
- Para evaluar el impacto de la suplementación de potasio frente al placebo en un diseño de estudio cruzado controlado.
Principales métodos:
- Un estudio aleatorizado, doble ciego y cruzado que involucró a 20 varones jóvenes y sanos.
- Los participantes recibieron 64 mmol de potasio oral por día o un placebo.
- El sodio en la dieta no estaba restringido, y los participantes seguían una dieta normal.
Principales resultados:
- Una proporción significativamente mayor de los participantes exhibió una menor presión arterial sistólica y diastólica durante la suplementación con potasio en comparación con el placebo.
- La presión arterial diastólica promedio se redujo significativamente en 2,4 mm Hg con la ingesta de potasio.
- Los cambios en la presión diastólica se correlacionaron negativamente con la excreción urinaria de potasio y positivamente con la relación sodio/potasio urinario.
Conclusiones:
- La suplementación oral de potasio puede reducir eficazmente la presión arterial en hombres jóvenes y sanos.
- Mantener una ingesta adecuada de potasio puede ser beneficioso para el control de la presión arterial.
- Las proporciones de electrolitos urinarios reflejan la respuesta del cuerpo a la suplementación con potasio.
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