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La inactivación del virus asociado a la linfadenopatía por desinfectantes químicos
Lancet (London, England)
|October 20, 1984
Resumen
Los desinfectantes químicos estándar inactivan efectivamente la transcriptasa inversa del virus asociado a la linfadenopatía (LAV). El etanol y el glutaraldehído se recomiendan para instrumentos médicos, mientras que el hipoclorito de sodio es adecuado para superficies.
Área de la Ciencia:
- Virología Virología.
- Enfermedades infecciosas Enfermedades infecciosas.
- Salud Pública La salud pública.
Sus antecedentes:
- El virus asociado a la linfadenopatía (VLA) es un patógeno humano significativo.
- Los protocolos de desinfección eficaces son cruciales para prevenir la transmisión de LAV en los entornos de atención médica.
Objetivo del estudio:
- Evaluar la eficacia de los desinfectantes químicos comunes contra la actividad de la transcriptasa inversa del LAV.
- Proporcionar recomendaciones basadas en la evidencia para la desinfección de LAV.
Principales métodos:
- Evaluación de la actividad de la transcriptasa inversa de LAV.
- Exponer el LAV a varias concentraciones de etanol, glutaraldehído, hipoclorito de sodio y formalina.
Principales resultados:
- El 25% de etanol y el 1% de glutaraldehído inactivaron efectivamente la transcriptasa inversa de LAV, lo que indica su idoneidad para la desinfección de instrumentos médicos.
- El hipoclorito de sodio al 0,2% demostró eficacia para la limpieza de pisos y bancos.
- El 0,1% de formalina mostró tasas de inactivación lentas y no se recomienda.
Conclusiones:
- Las concentraciones específicas de etanol, glutaraldehído e hipoclorito de sodio son desinfectantes efectivos contra el LAV.
- No se recomienda el uso de formalina debido a la cinética de inactivación lenta.
Palabras clave:
Síndrome de Inmunodeficiencia Adquirida Síndrome de Inmunodeficiencia AdquiridaLas bebidas alcohólicas.Enfermedades Las enfermedades.Exámenes y diagnósticos.Infecciones por el VIH Infecciones por el VIHExámenes de laboratorio y diagnósticos.Procedimientos de laboratorio Procedimientos de laboratorioProductos químicos orgánicos Productos químicos orgánicos.Enfermedades virales Las enfermedades virales.
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