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Updated: Jul 30, 2026

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Modo de activación proviral de un supuesto oncogén mamario (int-1) en el cromosoma 15 del ratón

R Nusse, A van Ooyen, D Cox

    Nature
    |January 12, 1984
    PubMed
    Resumen

    El virus del tumor mamario del ratón (MMTV) induce carcinomas mamarios en ratones a través de inserciones provirales cerca del gen int-1. Esta inserción activa el gen int-1, un potencial oncogén, en tumores pero no en tejidos normales.

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