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Updated: Oct 3, 2026

Monitoring the Assembly of a Secreted Bacterial Virulence Factor Using Site-specific Crosslinking
11:33

Monitoring the Assembly of a Secreted Bacterial Virulence Factor Using Site-specific Crosslinking

Published on: December 17, 2013

Requisito para la escisión del péptido de señal de la prolipoproteína de Escherichia coli

S Inouye, C P Hsu, K Itakura

    Science (New York, N.Y.)
    |July 1, 1983
    PubMed
    Resumen

    La alteración del sitio de escisión del péptido de señal de la lipoproteína de Escherichia coli mediante la sustitución de glicina por alanina no obstaculizó el procesamiento del péptido de señal. Sin embargo, la eliminación del residuo de glicina impidió la escisión del péptido de señal, destacando la necesidad de integridad estructural en este sitio para el procesamiento adecuado de la prolipoproteína.

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