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Videos de Conceptos Relacionados

Epistasis01:39

Epistasis

In addition to multiple alleles at the same locus influencing traits, numerous genes or alleles at different locations may interact and influence phenotypes in a phenomenon called epistasis. For example, rabbit fur can be black or brown depending on whether the animal is homozygous dominant or heterozygous at a TYRP1 locus. However, if the rabbit is also homozygous recessive at a locus on the tyrosinase gene (TYR), it will have an unshaded coat that appears white, regardless of its TYRP1...
Pleiotropy01:33

Pleiotropy

Pleiotropy is the phenomenon in which a single gene impacts multiple, seemingly unrelated phenotypic traits. For example, defects in the SOX10 gene cause Waardenburg Syndrome Type 4, or WS4, which can cause defects in pigmentation, hearing impairments, and an absence of intestinal contractions necessary for elimination. This diversity of phenotypes results from the expression pattern of SOX10 in early embryonic and fetal development. SOX10 is found in neural crest cells that form melanocytes,...
From DNA to Protein03:06

From DNA to Protein

The flow of genetic information in cells from DNA to mRNA to protein is described by the central dogma, which states that genes specify the sequence of mRNAs, which in turn specify the sequence of amino acids making up all proteins. The decoding of one molecule to another is performed by specific proteins and RNAs. Because the information stored in DNA is so central to cellular function, it makes intuitive sense that the cell would make mRNA copies of this information for protein synthesis...
Epistasis Analysis01:09

Epistasis Analysis

Although Mendel chose seven unrelated traits in peas to study gene segregation, most traits involve multiple gene interactions that create a spectrum of phenotypes. When the interaction of various genes or alleles at different locations influences a phenotype, this is called epistasis. Epistasis often involves one gene masking or interfering with the expression of another (antagonistic epistasis). Epistasis often occurs when different genes are part of the same biochemical pathway. The...
Structure of a Gene01:30

Structure of a Gene

A gene is the fundamental unit of heredity. Every individual has two copies of each gene, one inherited from each parent. Although most people contain the same genes, there is a small fraction that is slightly different amongst people. A gene with a small difference in its sequence of DNA bases forms different alleles, contributing to different phenotypes.
However, only 1% of the DNA is composed of genes that encode proteins; the rest, 99% is non-coding DNA. This non-coding DNA performs...
Inheritance01:25

Inheritance

Gregor Mendel's pioneering work on the principles of inheritance fundamentally transformed our understanding of how traits are transmitted from generation to generation. His experiments with pea plants laid the groundwork for the discovery of genes, discrete units within organisms that control heredity.
Each gene exists in pairs, and the combination of these genes from both parents forms an individual's genotype. This genotype is a blueprint of potential traits. Examples of genotype traits...

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Prospective randomised trial of the Integrated Pulmonary Index™ in low-acuity inpatients.

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Localization of phytic acid in the floral structure of Petunia hybrida and relation to the incompatibility genes.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·2013
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Self-incompatibility alleles control a low molecular weight, basic protein in pistils of Petunia hybrida.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·2013
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Gene flow in an almond orchard.

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Sweet cherry cultivar identification by leaf isozyme polymorphism.

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Video Experimental Relacionado

Updated: Jul 11, 2026

Paradigms for Pharmacological Characterization of C. elegans Synaptic Transmission Mutants
18:01

Paradigms for Pharmacological Characterization of C. elegans Synaptic Transmission Mutants

Published on: August 18, 2008

Un solo gen codifica múltiples neuropéptidos que median un comportamiento estereotipado.

R H Scheller, J F Jackson, L B McAllister

    Cell
    |January 1, 1983
    PubMed
    Resumen

    Los investigadores secuenciaron tres genes que controlan la puesta de huevos de Aplysia, revelando una familia multigénica que produce péptidos neuroactivos relacionados (A, B y hormona de puesta de huevos) para funciones distintas.

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    Last Updated: Jul 11, 2026

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    Área de la Ciencia:

    • La neurobiología es la neurobiología.
    • Biología Molecular Biología Molecular
    • Ciencias del comportamiento Ciencias del comportamiento.

    Sus antecedentes:

    • La puesta de huevos en Aplysia es un comportamiento complejo regulado por péptidos neuroactivos.
    • Los péptidos específicos, incluidos A, B y la hormona de puesta de huevos (ELH), están implicados en iniciar y mediar este comportamiento estereotipado.

    Objetivo del estudio:

    • Para secuenciar genes que codifican los péptidos A y B y la hormona de puesta de huevos (ELH).
    • Investigar la base genética y las relaciones evolutivas de estos genes peptídicos neuroactivos en Aplysia.

    Principales métodos:

    • Secuenciación genética de tres genes identificados.
    • Análisis de la homología de nucleótidos y divergencia de secuencias.
    • Examen de la estructura genética y el procesamiento de potenciales precursores de péptidos.

    Principales resultados:

    • Se secuenciaron tres genes homólogos que codifican los péptidos A, B y ELH, mostrando una homología de secuencia del 90%.
    • Cada gen codifica un precursor de proteína capaz de generar múltiples péptidos pequeños.
    • A pesar de la alta homología, los genes han divergido para expresar conjuntos de péptidos distintos y funcionalmente relacionados en diferentes tejidos.

    Conclusiones:

    • El sistema de puesta de huevos de Aplysia está controlado por una pequeña familia multigénica con secuencias conservadas pero divergentes.
    • La expresión génica diferencial permite la producción de péptidos neuroactivos específicos que median aspectos distintos del comportamiento de puesta de huevos.